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Description

Acyclovir is an antiviral agent that is active against the herpes virus infections of the genitals, skin, brain, and mucous membranes. The drug is also used to treat other viral infections such as sh ingles and chickenpox. Acyclovir is used both systematically and topically, but usually will only help with the symptoms and will not lead to a cure of the virus. Side effects include pain, swelling, increased thirst, loss of appetite, and nausea

Precautions while Using this Medicine

Before taking acyclovir,

- tell your doctor and pharmacist if you are allergic to acyclovir, valacyclovir (Valtrex), or any other drugs.
- tell your doctor and pharmacist what prescripti on and nonprescription medications you are taking, especially probenecid (Benemid), zidovudine (Retrovir, AZT), and vitamins.
- tell your doctor if you have or have ever had kidney disease, probl ems with your immune system, human immunodeficiency virus infection (HIV), or acquired immunodeficiency syndrome (AIDS).
- tell your doctor if you are pregnant, plan to become pregnant, or are br east-feeding. If you become pregnant while taking acyclovir, call your doctor.

Other Medicines

It is especially important that your health care professional know if you are taking any of the following:
- Carmustine (e.g., BiCNU) or
- Cisplatin (e.g., Platinol) or
- Combination pa in medicine containing acetaminophen and aspirin (e.g., Excedrin) or other salicylates or
- Cyclosporine (e.g., Sandimmune) or
- Deferoxamine (e.g., Desferal) (with long-term use) or
- Gold salts (medicine for arthritis) or
- Inflammation or pain medicine, except narcotics, or
- Lithium (e.g., Lithane) or
- Methotrexate (Mexate) or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine) or
- Plicamycin (e.g., Mithracin) or

What side effects may occur?

This medication may cause stomach upset, loss of appetite, nausea, vomiting, diarrhea, headache, dizziness or weakness. These effects should disappear in a few days as your body adjusts to the medicat ion. If they persist or become worse, inform your doctor. Notify your doctor if you experience: numbness or tingling of the hands or feet, leg pain, sore throat, skin rash, change in the amount of uri ne. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. I f you notice other effects not listed above, contact your doctor or pharmacist.

Symptoms of overdose may include:

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness ¡K

What special precautions should I follow?

Other medicines¡XAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your do or may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) me dicine that is to be applied to the same area of the skin.

Other medical problems¡XTell your doctor if your herpes simplex infection keeps coming back while you are using acyclovir


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