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Stop Using This Medicine

If you will be taking zolpidem for a long time, do not stop taking it without first checking with your doctor. Your doctor may want you to reduce gradually the amount you are taking before stopping co mpletely. Stopping this medicine suddenly may cause withdrawal side effects.

After taking zolpidem for insomnia, you may have difficulty sleeping (rebound insomnia) for the first few nights a fter you stop taking it



Cautions

Sleep medicines may cause a special type of memory loss or ``amnesia''. When this occurs, a person does not remember what has happened during the several hours between use of the medicine and the time when its effects wear off. This is usually not a problem since most people fall asleep after taking the medicine. In most instances, memory problems can be avoided by taking zolpidem only when you ar e able to get a full night's sleep (7 to 8 hours) before you need to be active again. Be sure to talk to your doctor if you think you are having memory problems.



Possible food and drug interactions when taking this medication

It is especially important that your health care professional know if you are taking any of the following:

- Other central nervous system (CNS) depressants (medicines that cause drowsiness) or
- Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g. , Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil])ˇXThe CNS depressant effects of either these medicines or zolpidem may be increased, possibly leading to unwanted effects

Why is this medication prescribed?

Zolpidem (ZOLE-pi-dem) belongs to the group of medicines called central nervous system (CNS) depressants (medicines that slow down the nervous system). Zolpidem is used to treat insomnia (trouble in s leeping). Zolpidem helps you get to sleep faster and sleep through the night. In general, when sleep medicines are used every night for a long time, they may lose their effectiveness. In most cases, s leep medicines should be used only for short periods of time, such as 1 or 2 days, and generally for no longer than 1 or 2 weeks.



Precautions while Using this Medicine

If you think you need to take zolpidem for more than 7 to 10 days, be sure to discuss it with your doctor. Insomnia that lasts longer than this may be a sign of another medical problem.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or a nesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.


What side effects can this medication cause?

Although side effects from zolpidem are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- drowsiness
- upset stomach
- vomiting
- constipation
- diarrhea
- headache
- dry mouth
- muscle aches

If you experience any of the following symptoms, call your doctor immediately:

- skin rash
- itching
- fast or irregular heartbeat
- chest pain
- difficulty breathing
- fever
- behavior changes
- mental confusion
- abnormal thinking or dreams
- d epression




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