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Why is this medication prescribed?

Tenuate, an appetite suppressant, is prescribed for short-term use (a few weeks) as part of an overall diet plan for weight reduction. It is available in two forms: immediate-release tablets (Tenuate) and controlled-release tablets (Tenuate Dospan). Tenuate should be used with a behavior modification program.

How should this medicine be used?

Tenuate comes as a regular and extended-release (long-acting) tablet. Tenuate usually is taken three times a day, 1 hour before meals (regular tablets), or once a day in midmorning (extended-release t ablets). Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Tenuate exactly as directed.

Do not crus h, chew, or cut extended-release tablets; swallow them whole.

Tenuate may be habit-forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to . Call your doctor if Tenuate loses its effect.

What side effects can this medication cause?

Side effects may include:
- Abdominal discomfort, abnormal redness of the skin, anxiety, blood pressure elevation, blurred vision, breast development in males, bruising, changes in sex drive, che st pain, constipation, depression, diarrhea, difficulty with voluntary movements, dizziness, drowsiness, dryness of the mouth, feelings of discomfort, feelings of elation, feeling of illness, hair los s, headache, hives, impotence, inability to fall or stay asleep, increased heart rate, increased seizures in epileptics, increased sweating, increased volume of diluted urine, irregular heartbeat, jit teriness, menstrual upset, muscle pain, nausea, nervousness, overstimulation, painful urination, palpitations, pupil dilation, rash, restlessness,

Other medical problems

ChildrenˇXStudies on these medicines have been done only in adult patients, and there is no specific information comparing use of Tenuate in children with use in other age groups. The use of these medi cines by children younger than 16 years of age is not recommended.

Older adultsˇXMany medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of appetite suppressants in the elderly with use in other age groups.

Possible food and drug interactions

Tenuate or Tenuate Dospan may interact with alcohol unfavorably. Do not drink alcohol while taking this medication.

If Tenuate or Tenuate Dospan is taken with certain other drugs, the effect s of either could be increased, decreased, or altered. It is especially important that you consult your doctor before combining Tenuate with the following:

- Blood pressure medications such as Ismelin
- Insulin
- Phenothiazine drugs such as the major tranquilizer Thorazine

Precautions while Using this Medicine

If you have been taking this medicine for a long time or in large doses and you think you may have become mentally or physically dependent on it, check with your doctor.

- Some signs of depe ndence on appetite suppressants are:
- a strong desire or need to continue taking the medicine.
- a need to increase the dose to receive the effects of the medicine.
- withdrawal side e ffects (for example, mental depression, nausea or vomiting, stomach cramps or pain, trembling, unusual tiredness or weakness) when you stop taking the medicine


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