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The Texas Department of Health (TDH), has proposed banning certain ephedra and ephedrine-containing products made by dietary supplement companies, while preserving products of the pharmaceutical indus
try. This interesting--if a bit convoluted--proposal seeks to make the following changes in regulating products in the state of Texas:
-All ephedrine products would become prescription drugs, exce
pt:
-Ephedra (ma huang) products would be exempt only if they are less than 3% alkaloid (read "NO EXTRACTS").
-It would be illegal to sell any ephedra or ephedrine-containing product in combin
ation with combinations with caffeine or caffeine-containing plants including cola, tea or guarana.
-A list of over-the-counter (OTC) drugs made by pharmaceutical companies would be specifically e
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These terms are used to refer to the same substance derived from the plant Ephedra. (There are many common names for these evergreen plants, including squaw tea and Mormon tea.) Ephedra is a shrub-lik
e plant that is found in desert regions in central Asia and other parts of the world. The dried greens of the plant are used medicinally. Ephedra is a stimulant containing the herbal form of ephedrine
, an FDA-regulated drug found in over-the-counter asthma medications.
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Ephedrine is the oral form of Epinephrine, or adrenaline. It was
-once a commonly prescribed drug for asthma, but newer drugs in the
-xanthine class have less side effects.
-Ephedrine is rela
ted to pseudoephedrine which was designed as a
-decongestant with less undesirable effects.
-Ephedra is a Chinese herb that's been used for centuries to treat
-asthma
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Ephedrine alkaloids are amphetamine-like compounds used in OTC and prescription drugs with potentially lethal stimulant effects on the central nervous system and heart. The FDA has received more than
800 reports of adverse effects associated with use of products containing ephedrine alkaloid since 1994. These serious adverse effects, include hypertension (elevated blood pressure), palpitations (ra
pid heart rate), neurophathy (nerve damage), myopathy (muscle injury), psychosis, stroke, memory loss, heart rate irregularities, insomnia, nervousness, tremors, seizures, heart attacks, and death. Th
e agency has proposed to prohibit the marketing of dietary supplements containing 8 milligrams or more of ephedrine alkaloids per serving.
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Ephedrine has moderately potent bronchial muscle relaxant properties, and
-therefore is used for symptomatic relief in milder cases of asthmatic
-attack; it is also used to reduce the risk of ac
ute attacks in the treatment
-of chronic asthma. The typical adult dose range is 30-60 mg taken orally,
-three to four times per day, in the form of tablets. Ephedrine in the form
-of nose dr
ops is also widely used to relieve nasal congestion associated
-with upper respitory tract illnesses. It is also used to treat low blood
-pressure, because it constricts blood vessels and stimul
ates certain actions
-of the heart. Common side effects are qualitatively similar to those
-produced by amphetamines and are generally milder.
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Ephedrine act as stimulants that can cause rapid or irregular heartbeats (heart arrhythmias) Ephedrines act in a similar way as that of adrenaline. It dilates the bronchial muscles, contacts the nasal
mucosa, raises the blood pressure and is a cardiac stimulant. Further these compounds often cause psychological side effects such as depression, nervousness, insomnia, and rapid heart rate. When take
n in combination with caffeine, ephedrine can over-stimulate the central nervous system, leading to potentially life-threatening results.
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