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Ephedrine is an adrenergic drug that works by stimulating alpha
-and beta receptors thus causing the release of norepinephrine.
-Alpha and beta receptors exist in the sympathetic nervous system,
-(fight or flight) and stimulation causes increased heart rate,
-bronchodilation, and vasoconstriction.

The Texas Department of Health (TDH), has proposed banning certain ephedra and ephedrine-containing products made by dietary supplement companies, while preserving products of the pharmaceutical indus try. This interesting--if a bit convoluted--proposal seeks to make the following changes in regulating products in the state of Texas:
-All ephedrine products would become prescription drugs, exce pt:
-Ephedra (ma huang) products would be exempt only if they are less than 3% alkaloid (read "NO EXTRACTS").
-It would be illegal to sell any ephedra or ephedrine-containing product in combin ation with combinations with caffeine or caffeine-containing plants including cola, tea or guarana.
-A list of over-the-counter (OTC) drugs made by pharmaceutical companies would be specifically e

What is ephedrine? Ephedrine (e-fed¡¦rin) a-methylamino-l phenyl-l propanol, is an alkaloid from the leaves of Ephededra equisetina, E. Sinica, and other species (family Gnetaceae). It is also called E phedra & Ma Huang, the plant source for the Alkaloid ephedrine. Indigenous to China, India and parts of SoutheastAsia . Products containing ephedrine extracts have according to the FDA, caused hundred s of illnesses, including heart attacks, seizures, strokes and even 15 reported deaths. They are amphetamine-like compounds with powerful and potentially lethal stimulant effects on the central nervou s system and the heart.

Ephedra's main active medical ingredients are the alkaloids ephedrine and pseudoephedrine. The ephedras also contain various tannins and related chemicals.The stem contains 1-3% total alkaloids, with ephedrine accounting for 30-90% of this total. The concentrations of these alkaloids depends upon the particular species of ephedra used.

Ephedrine is the active ingredient in many diet pills and supplements. Many use the name "thermo", "lean" or "fat burner." Brand names include, Metabolife, MeTrim, Herbalife, Adiphen, Thermalean, Lipo drene, Zymax, Genicil, Patent Lean, Thermoslim, Ultra Lipo Lean, Trim Life, Hydroxy Cut, Xenadrine, Herbal Phen-Fen, Shapefast, Thermoburn, Thyro-slim, Trim Spa, Natural Trim, Thermo-Lift and many oth ers.

Ephedrine alkaloids are amphetamine-like compounds used in OTC and prescription drugs with potentially lethal stimulant effects on the central nervous system and heart. The FDA has received more than 800 reports of adverse effects associated with use of products containing ephedrine alkaloid since 1994. These serious adverse effects, include hypertension (elevated blood pressure), palpitations (ra pid heart rate), neurophathy (nerve damage), myopathy (muscle injury), psychosis, stroke, memory loss, heart rate irregularities, insomnia, nervousness, tremors, seizures, heart attacks, and death. Th e agency has proposed to prohibit the marketing of dietary supplements containing 8 milligrams or more of ephedrine alkaloids per serving.


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