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Serious, potentially fatal reactions may occur if you take Flexeril with an antidepressant drug known as an MAO inhibitor (such as Nardil, Parnate) or if it has been less than 2 weeks since you last t ook an MAO inhibitor. You should closely follow your doctor's advice regarding discontinuation of MAO inhibitors before taking Flexeril.

Avoid alcoholic beverages while taking Flexeril.
< br> If Flexeril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Flexeril with the following:

- Guanethidine and other high blood pressure drugs
- Other drugs that slow the central nervous system
- Tramadol (Ultram)

Other medical problems

Children¡XStudies on this medicine have been done only in adult patients, and there is no specific information comparing use of cyclobenzaprine in children with use in other age groups.

How should this medicine be used?

Flexeril may be taken with or without food. Flexeril should be used only for short periods (no more than 3 weeks). Since the type of injury that Flexeril treats should improve in a few weeks, there is no reason to use it for a longer period. Flexeril may cause dry mouth. Sucking a hard candy, chewing gum, or melting ice chips in your mouth can provide temporary relief.

Cautions

The effects of Flexeril during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known if Flexeril appears in breast milk. However, cyclobenzaprine is related to tricyclic antidepressants, and some of those drugs do appear in breast milk. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding your baby until your treatment is finished.

What is this medicine

Cyclobenzaprine, a muscle relaxant, is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.

Overdosage

Convulsions (seizures); drowsiness (severe) ; dry, hot, flushed skin; fast or irregular heartbeat; hallucinations (seeing, hearing, or feeling things that are not there); increase or decrease in body temperature; troubled breathing; unexplained muscle stiffness; unusual nervousness or restlessness (severe); vomiting (occurring together with other symptoms of overdose)


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