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Precautions Before Using This Medicine

Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil ], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil])¡XHigher blood levels of these medicines may occur, which may increase the chance of developing unwante effects. Your doctor may check the blood level of the tricyclic antidepressant, and may change the dose of either these medicines or Zoloft. Also, taking Zoloft with amitriptyline, clomipramine, or i mipramine may increase the chance of developing the serotonin syndrome

Side Effects

Less common or rare side effects may include:
- frequent urination, hair loss, heart attack, hemorrhoids, hiccups, high blood pressure, high pressure within the eye (glaucoma), hearing problems, hot flushes, impotence, inability to stay seated, increased appetite, increased salivation, increased sex drive, inflamed nasal passages, inflammation of the penis, intolerance to light, irregular he artbeat, itching, joint pains, kidney failure, lack of coordination, lack of sensation, leg cramps, menstrual problems, low blood pressure, migraine, movement problems,

What is this medicine

Zoloft can also be used for the type of depression called premenstrual dysphoric disorder (PMDD). This recurring problem is marked by a depressed mood, anxiety or tension, emotional instability, and a nger or irritability in the two weeks preceding menstruation. Other symptoms may include loss of interest in activities, difficulty concentrating, lack of energy, changes in appetite or sleep patterns , and feeling out of control.

How to Use

Zoloft is available in capsule and oral concentrate forms. To prepare Zoloft oral concentrate, use the dropper provided. Measure out the amount of concentrate prescribed by your doctor and mix it with 4 ounces of water, ginger ale, lemon/lime soda, lemonade, or orange juice. (Do not mix the concentrate with any other type of beverage.) Drink the mixture immediately; do not prepare it in advance fo r later use. At times, a slight haze may appear after mixing, but this is normal.

Improvement with Zoloft may not be seen for several days to a few weeks. You should expect to keep taking it for at least several months.

Zoloft may make your mouth dry. For temporary relief suck a hard candy, chew gum, or melt bits of ice in your mouth.

Management of Overdoses:


- hair loss
- changes in sex drive or ability
- drowsiness
- excessive tiredness
- difficulty falling asleep or staying asleep
- diarrhea
- vomiting
- rapid pou nding or irregular heartbeat
- upset stomach
- dizziness
- excitement
- tremor
- coma
- seizures
- hearing voices or seeing things that do not exist (hallucinating)
- unconsciousness
- fainting

Special Wanring

Central and Peripheral Nervous System Disorders: - Frequent: Confusion. Infrequent: Ataxia, abnormal coordination, abnormal gait, hyperesthesia, hyperkinesia, hypokinesia, migraine, nystagmus, vertigo . Rare: Local anesthesia, coma, convulsions, dyskinesia, dysphonia, hyporeflexia, hypotonia, ptosis.


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